Learn how our investigational therapies work

1. Engineer

2. Shield

3. Prepare

4. Place

5. Produce

  • 1 Engineer

    Our investigational therapies start with human cells engineered to produce clotting factors, hormones, enzymes or other proteins that are missing or deficient.

  • 2 Shield

    We then put the cells into tiny spheres. These special spheres do two things:

    • Shield the cells from your body’s immune system, preventing them from being attacked.
    • Allow the inflow of nutrients and the outflow of a specific therapy

    Fast Fact: 20,000 to 40,000 cells fit into one sphere. Each sphere is 1.5 mm in diameter.

  • 3 Prepare

    Here’s what a potential dose could look like. For purposes of this visualization, we have colored the spheres blue, but in reality, they are clear.

  • 4 Place

    For our clinical studies, a doctor will place the spheres into your abdomen via a minimally invasive procedure. Protected by the shielded spheres, the cells are designed to live where they are placed, producing the specific protein you need, which will then circulate throughout the body.

  • 5 Produce

    The cells are designed to produce sustained, long-lasting levels of the therapeutic protein. This technology allows us to re-dose if necessary.

We Care

At Sigilon, we care deeply about patients and caregivers; they are at the center of what we do and how we act. Below are some recent ways Sigilon and its’ employees have shown their commitment to the communities we hope to serve.

Serving the community