Senior Scientist, Chemistry

Sigilon Therapeutics is a multidisciplinary biotechnology company which specializes in creating immune privileged products to address unmet clinical needs. Our mission at Sigilon Therapeutics is to create immune-protected, engineered human cells that restore normal physiology in a wide range of diseases without generating fibrosis or immune rejection, liberating patients from challenges associated with serious chronic diseases. We are based in Kendall Square in Cambridge, MA, and funded by Flagship Pioneering. Please send your application via email to

Sigilon Therapeutics seeks a highly motivated, energetic, and results-driven organic chemist to join its chemistry group. The role will consist of laboratory work in support of the chemistry team’s efforts to design, synthesize, and optimize reactions around Sigilon’s proprietary Afibromer® technology. This person will assist in the development of small molecules, polymers, and medical devices with both established and novel techniques. This role will require regular interaction with stake holders in many disciplines and the presentation of written and oral summaries of progress the chemistry group. Sigilon Therapeutics operates with a typical hybrid of internal and external resources and maintains a safe laboratory environment. Experience in polymer synthesis and manipulation is preferred but not required.