We are seeking versatile scientists to help us create immune privileged products that address unmet clinical needs.


  • We look for employees who are intellectually curious, willing to ask questions and take measured risks. When an employee joins Sigilon Therapeutics, they become part of the Sigilon Therapeutics family.

  • The ability for prospective employees to fit within the Sigilon Therapeutics culture is a critical consideration.


Sigilon Therapeutics is a multidisciplinary biotechnology company which specializes in creating immune privileged products to address unmet clinical needs.

Sigilon Therapeutics’s technology has the ability to completely transform how we treat patients with chronic diseases. Originated from Robert Langer and Daniel Anderson’s laboratories of MIT and was patented and published in three seminal reports in Nature Materials, Nature Biotechnology, and Nature Medicine in 2015 and 2016. The company is based in Cambridge, MA and is funded by Flagship Pioneering. Now is the time to get in on the ground floor of a fast growing company with a very interactive and open culture.

Please forward your application via email to careers@sigilon.com

    Current Openings

  • Biomedical Process Design Engineer

    Development and scale-up of cell-loaded hydrogel microsphere production process, integration of imaging inspection system into manufacturing process and more.

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  • Process Chemistry Scientist

    Sigilon Therapeutics seeks a highly motivated, energetic, and results-driven process chemist or engineer to join its chemistry group. The role will consist of laboratory work in support of the chemistry team’s efforts to design, synthesize, and optimize reactions around Sigilon’s proprietary Afibromer® technology.

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  • Research Associate (Biomaterials)

    Research Associate with tissue culture experience of primary cells and cell line, encapsulation of cells in novel biopolymer systems, maintenance and setting up of encapsulation systems.

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  • Research Associate (Cell Culture)

    Make a difference and join Sigilon in the capacity of Research Associate.  This position requires tissue culture of primary cells and cell lines, stable transfection and viability cell-based assays and more.

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  • Research Associate (Diabetes)

    Sigilon Therapeutics is searching for a seasoned Research Associate to join the team.  Experience with tissue culture of primary cells and pluripotent stem cells, stable transfection and selection of engineered cell lines as well as experience with stem cell differentiation protocols, preferably in Diabetes area are a plus.

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  • Senior Research Associate (Assays)

    Sigilon Therapeutics is seeking an experienced Senior Research Associate to join a new team that develops and delivers biological assays for multiple therapeutic programs across the company.

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  • Senior Research Associate (in vivo)

    Sigilon Therapeutics is seeking an individual with broad expertise in in-vivo and translational biology, excellent communication skills, and the ability to work in a highly interactive and matrixed environment.

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  • Senior/Research Associate, Analytical Chemist

    The Research Associate will be responsible for running and developing methods to characterize small molecules, polymers, and formulated mixtures with both established and novel techniques.

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  • Sr Director CMC - Islet Cell Therapy

    Sigilon Therapeutics is searching for an energized candidate to lead a new team focused on CMC and manufacturing a novel therapeutic product for diabetes utilizing Sigilon’s Afibromer™ technology combined with leading edge pancreatic islet cell technology.

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  • Talent Acquisition/HR Partner

    Reporting to the VP, Human Resources, the Talent Acquisition/HR Partner is responsible for designing and implementing all hiring processes and systems for the company.

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Why work at Sigilon Therapeutics?

We provide a competitive salary and benefits package to our employees. Benefits include: a 401K plan, paid time off, health and dental insurance. We want our employees to love their work environment and enjoy working with their colleagues.

Team SigilonTX, June 2018


Team SigilonTX, June 2017