We are seeking versatile scientists to help us create immune privileged products that address unmet clinical needs.


  • We look for employees who are intellectually curious, willing to ask questions and take measured risks. When an employee joins Sigilon Therapeutics, they become part of the Sigilon Therapeutics family.

  • The ability for prospective employees to fit within the Sigilon Therapeutics culture is a critical consideration.


Sigilon Therapeutics is a multidisciplinary biotechnology company which specializes in creating immune privileged products to address unmet clinical needs.

Sigilon Therapeutics’s technology has the ability to completely transform how we treat patients with chronic diseases. Originated from Robert Langer and Daniel Anderson’s laboratories of MIT and was patented and published in three seminal reports in Nature Materials, Nature Biotechnology, and Nature Medicine in 2015 and 2016. The company is based in Cambridge, MA and is funded by Flagship Pioneering. Now is the time to get in on the ground floor of a fast growing company with a very interactive and open culture.

Please forward your application via email to careers@sigilon.com

    Current Openings

  • Biomedical Process Design Engineer

    Development and scale-up of cell-loaded hydrogel microsphere production process, integration of imaging inspection system into manufacturing process and more.

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  • Director of Islet Cell Biology

    Sigilon Therapeutics is searching for an energized candidate to help develop and execute on a program focused on allogeneic stem-cell derived pancreatic islet cells for treatment of diabetes. We seek a senior level scientist who is an expert in islet cell biology to further the work on this important therapy. Expertise in beta cell differentiation from hESC or iPSC cells is a critical aspect of the position.

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  • Director, New Product Planning

    Sigilon is looking for a Director of New Product Planning to lead our efforts as we work to build out our pipeline of indications.  This role is accountable for market assessments and competitive oversight for existing and new indications for the company.

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  • Research Associate (Biomaterials)

    Research Associate with tissue culture experience of primary cells and cell line, encapsulation of cells in novel biopolymer systems, maintenance and setting up of encapsulation systems.

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  • Research Associate (Cell Culture)

    Make a difference and join Sigilon in the capacity of Research Associate.  This position requires tissue culture of primary cells and cell lines, stable transfection and viability cell-based assays and more.

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  • Research Associate (Diabetes)

    Sigilon Therapeutics is searching for a seasoned Research Associate to join the team.  Experience with tissue culture of primary cells and pluripotent stem cells, stable transfection and selection of engineered cell lines as well as experience with stem cell differentiation protocols, preferably in Diabetes area are a plus.

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  • Research Associate, Analytical Chemist

    This person will run methods to characterize small molecules, polymers, and formulated mixtures with both established and novel techniques.

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  • VP CMC/Manufacturing Diabetes Research Group

    Sigilon Therapeutics is searching for an energized candidate to lead a new team focused on CMC and manufacturing a novel therapeutic product for diabetes utilizing Sigilon’s Afibromer™ technology combined with leading edge pancreatic islet cell technology.  This individual would have primary responsibility for all aspects of CMC and manufacturing including: process development, analytical development, CMC, and QA. Initial emphasis will be on partnering with the research team to create a protocol that can be transferred to a CMO.  In addition, qualifying, negotiating with and oversight of a CMO is critical.  The team will have full access to all of Sigilon’s cell biology and encapsulation chemistry expertise along with substantial designated funds to enable a rapid pursuit of a very robust and competitive program.

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Why work at Sigilon Therapeutics?

We provide a competitive salary and benefits package to our employees. Benefits include: a 401K plan, paid time off, health and dental insurance. We want our employees to love their work environment and enjoy working with their colleagues.

Team SigilonTX, June 2018


Team SigilonTX, June 2017