Join a team that is making a true difference for patients

Culture

  • We are change-makers, and we never stop in our quest to advance therapies for patients in need.

  • We are a close-knit team with an upbeat atmosphere, and it shows in our productive science — a true team effort.

Sigilon Therapeutics is a multidisciplinary biotechnology company which specializes in creating immune privileged products to address unmet clinical needs.

Our mission at Sigilon Therapeutics is to create immune-protected, engineered human cells that restore normal physiology in a wide range of diseases without generating fibrosis or immune rejection, liberating patients from challenges associated with serious chronic diseases. We are based in Kendall Square in Cambridge, MA, and funded by Flagship Pioneering.

Please send your application via email to careers@sigilon.com

    Current Openings

  • Accounts Payable Clerk (part-time)

    Sigilon Therapeutics, Inc. is looking to add a part-time AP Clerk to our growing staff. The AP Clerk will report directly to the AP Accountant and will be responsible for general accounting responsibilities among other tasks.

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  • Assistant Scientist/Associate Scientist, Cell Biology

    The ideal candidate will transition easily into the tissue culture of primary cells and cell lines as well as the stable transfection and selection of engineered cell lines and more.

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  • Principal / Senior Associate Scientist, Assays

    Sigilon Therapeutics is seeking an experienced  Senior Associate Scientist to join a new team that develops and delivers biological assays for multiple therapeutic programs across the company.

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  • Scientist, Biomaterials

    Sigilon Therapeutics is seeking a Scientist, Biomaterials to join the team!

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  • Scientist, Process Development

     

    As our lead programs advance into clinical development in 2019, Sigilon is looking for experienced process development scientists to join the team responsible for enhancing and evolving the manufacturing process for Sigilon’s encapsulated allogeneic cell therapy platform. Key objectives will be to develop robust and scalable cell therapy bioprocesses and transfer these processes to contract manufacturing partners.

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  • Senior Director CMC, Islet Cell Therapy

    Sigilon Therapeutics is searching for an energized candidate to lead a new team focused on CMC and manufacturing a novel therapeutic product for diabetes utilizing Sigilon’s Afibromer™ technology combined with leading edge pancreatic islet cell technology.

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  • Senior Director, Supply Chain Management

    Sigilon Therapeutics is searching for an energized candidate to manage our external manufacturing supply chain. This role is responsible for planning, forecasting and ensuring supply of clinical drug product as well as managing clinical trial drug product shipments and scheduling. The position will entail building strong cross-functional relationships throughout the organization as well as managing a complex external manufacturing supply chain.

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  • Senior Mechanical Engineer

    The incumbent will be responsible for developing and performing methods to characterize laparoscopic delivery devices and equipment. The successful candidate will also assist in the development of methods to characterize hydrogel-based tissue scaffolds. This role will require daily interaction with stake holders in engineering, biology, and surgery. Presentation of written and oral summaries of progress in team meetings, as well as to management is expected. This employee will operate a diverse array of analytical equipment and maintain a safe laboratory environment

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  • Senior Process Engineer

    As our lead programs advance into clinical development in 2019, Sigilon is looking for an experienced process development scientist to lead the team responsible for enhancing and evolving the manufacturing process for Sigilon’s encapsulated allogeneic cell therapy platform. Key objectives will be to develop robust and scalable cell therapy bioprocesses and transfer these processes to contract manufacturing partners.

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  • Senior Scientist, Chemistry

    Sigilon Therapeutics seeks a highly motivated, energetic, and results-driven organic chemist to join its chemistry group. The role will consist of laboratory work in support of the chemistry team’s efforts to design, synthesize, and optimize reactions around Sigilon’s proprietary Afibromer® technology. This person will assist in the development of small molecules, polymers, and medical devices with both established and novel techniques. This role will require regular interaction with stake holders in many disciplines and the presentation of written and oral summaries of progress the chemistry group. Sigilon Therapeutics operates with a typical hybrid of internal and external resources and maintains a safe laboratory environment. Experience in polymer synthesis and manipulation is preferred but not required.

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  • Senior Scientist, Process Development

    As our lead programs advance into clinical development in 2019, Sigilon is looking for experienced process development scientists to join the team responsible for enhancing and evolving the manufacturing process for Sigilon’s encapsulated allogeneic cell therapy platform. Key objectives will be to develop robust and scalable cell therapy bioprocesses and transfer these processes to contract manufacturing partners.

    learn more  

  • Vice President, Head of Regulatory Affairs

    The Head of Regulatory Affairs will be the senior regulatory strategist supporting Sigilon’s assets entry into clinical trials by leading, developing and implement regulatory plans to meet company goals and objectives. This is an exciting opportunity to step into a newly created role reporting directly into Sigilon’s Chief Medical Officer.

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Why work at Sigilon Therapeutics?

We provide a competitive salary and benefits package to our employees. Benefits include: a 401K plan, paid time off, health and dental insurance. We want our employees to love their work environment and enjoy working with their colleagues.

Team SigilonTX, June 2018

 

Team SigilonTX, June 2017